You could take creatine at night (good for aging and sleep) which would suck water into your muscle tissue, which might make you need to pee less at night.
At ESC 2024, Bed-Med and Bed-Med Frail (2 new RCTs of BP med timing) were presented, as well as a new meta analysis which included those 2 studies and the earlier ones you mentioned. Iirc, the upshot was that the timing did not have an impact on clinical outcomes. However, I don’t think the relevant papers have yet been published.
Anecdotally, I ran a self experiment with bedtime anti-hypertensive medication with the exception of chlorthalidone and satin. I found a more even BP control with my oscillating pressure. If it is working, don't fix it. :) For me anyway...
I'm fortunate that I don't need blood pressure medication , but I do take two statins. It was suggested they might be more effective taken with an evening meal, but that is inconvenient, since my meal time varies and I'm not enthusiastic about pill-taking in restaurants. My cardiologist okayed taking them in the morning and they appear to be equally effective for me
Just an idea that popped into my head randomly...
You could take creatine at night (good for aging and sleep) which would suck water into your muscle tissue, which might make you need to pee less at night.
At ESC 2024, Bed-Med and Bed-Med Frail (2 new RCTs of BP med timing) were presented, as well as a new meta analysis which included those 2 studies and the earlier ones you mentioned. Iirc, the upshot was that the timing did not have an impact on clinical outcomes. However, I don’t think the relevant papers have yet been published.
Thanks for the latest update in this area! It confirms what I've gleaned over the last 6 years.
I like the study titles!
Anecdotally, I ran a self experiment with bedtime anti-hypertensive medication with the exception of chlorthalidone and satin. I found a more even BP control with my oscillating pressure. If it is working, don't fix it. :) For me anyway...
Excellent! I am a big fan of self (or physician-guided) adjustment in anti-hypertensive medication timing, dosing, and type
I'm fortunate that I don't need blood pressure medication , but I do take two statins. It was suggested they might be more effective taken with an evening meal, but that is inconvenient, since my meal time varies and I'm not enthusiastic about pill-taking in restaurants. My cardiologist okayed taking them in the morning and they appear to be equally effective for me
I hope you are not really taking two statins. That would be odd.
But the two most prescribed statins, atorvastatin and rosuvastatin have long half-lives and they don’t need to be taken at bedtime.
these posts are super helpful - thank you